Posts by: Jose Marques Lopes, PhD

News

Low-dose photon irradiation, commonly used in radiotherapy, potentially helps malignant pleural mesothelioma (MPM) cells spread, warns a study by Germany’s University of Heidelberg. The study, “Low-dose photon irradiation induces invasiveness through the SDF-1α/CXCR4 ... Read more

August 7, 2017August 7, 2017

Apitolisib Shows Promising Clinical Benefit in 2 Young Women with Peritoneal Mesothelioma, Study Shows

News

Treatment with the anti-cancer agent apitolisib has helped two patients with peritoneal mesothelioma (MPeM), a British study shows. The study, “Indolent peritoneal mesothelioma: PI3K-mTOR inhibitors as a novel therapeutic strategy,” appeared in ... Read more

July 5, 2017July 5, 2017

First MPM Patient Dosed in Keytruda, CRS-207 Combo Phase 2 Trial, Aduro Says

News

Aduro Biotech has tested a novel combination treatment for malignant pleural mesothelioma (MPM) in the first patient of a Phase 2 trial (NCT03175172). MPM is the most prevalent form of ... Read more

June 20, 2017

New Way to Promote Cell Death Could Lead to Better Mesothelioma Therapies, Study Reports

News

Activating a new mechanism to promote cell death could provide hope for better mesothelioma treatments, a Japanese study indicates. The research, ”Connexin 43 enhances Bax activation via JNK activation in ... Read more

March 22, 2017March 22, 2017

Tumor Thickness May Help Identify Mesothelioma Patients Needing Aggressive Treatment

News

Measuring tumor thickness may help doctors do a better job of determining which patients should have aggressive treatments for malignant pleural mesothelioma (MPM), research shows. The study, “Impact of tumour ... Read more

March 17, 2017March 17, 2017

Tissue-sparing Mesothelioma Surgery Generates Better Outcomes, Study Reports

News

Mesothelioma surgery that spares a patient’s lungs and diaphragm leads to better overall survival rates than surgery that removes part of the lungs and diaphragm, according to Italian surgeons. The ... Read more