Posts by: Stacy Grieve, PhD

News

Combining Ibrance with drugs that inhibit the PI3K pathway was found to stop the growth of malignant pleural mesothelioma (MPM) cells more effectively than treatment with Ibrance alone. Findings from the study, “Combined ... Read more

July 13, 2017July 27, 2017

Asbestos Substitute, Rock Wool Fiber, May Also Cause DNA Damage, Study Finds

News

An asbestos alternative known as rock wool fiber may also cause DNA damage, according to a laboratory study conducted in China. The finding may be important because scientists say asbestos causes the lung ... Read more

June 7, 2017

Nintedanib-Chemo Combo Increases Mesothelioma Patients’ Disease-Progression-Free Period

News

Adding nintedanib to chemotherapy led to a 64 percent increase in the time it took for mesothelioma patients’ disease to progress, compared with chemo alone, according to updated results of ... Read more

May 10, 2017May 10, 2017

Orally Available Small Molecule Inhibitor of SCD1 Targets Mesothelioma Metabolism, Study Finds

News

New preclinical research shows that T-3764518, an orally available small molecule inhibitor of stearoyl-CoA desaturate-1 (SCD1), can block tumor growth in colon cancer and mesothelioma cell lines as well as ... Read more

May 8, 2017May 8, 2017

Doll Factories Pose Occupational Hazard for Asbestos Exposure, Italian Study Finds

News

Women who work in cloth doll factories are exposed to asbestos and therefore have a higher risk of developing mesothelioma, an Italian study found. The report, “Pleural mesothelioma in doll ... Read more

May 1, 2017

Gene Could Become Path to Mesothelioma Therapies, Study Reports

News

A gene known as platelet-derived growth factor receptor beta (PDGFRB) could become the basis of therapies for malignant pleural mesothelioma (MPM), according to an early preclinical study. The research, “Inhibition ... Read more

April 26, 2017

Certain Prognostic Factor Can Predict Survival in Pleural Mesothelioma Patients, Analysis Finds

News

A comprehensive review of the literature concludes that the neutrophil-to-lymphocyte ratio (NLR) is a factor can be used to predict overall survival in patients with malignant pleural mesothelioma (MPM). The ... Read more