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July 28, 2017July 28, 2017

AstraZeneca’s Mesothelioma Therapy Tremelimumab Disappoints in Phase 2b Clinical Trial

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A Phase 2b clinical trial of AstraZeneca’s mesothelioma therapy tremelimumab showed no significant difference in survival times between treated and untreated patients. In addition, five of the treated patients — or 1 percent — ... Read more

July 27, 2017July 27, 2017

MPM Avastin and Pemetrexed/Cisplatin Combo Therapy May Not Make Economic Sense for Chinese Patients, Study Says

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Adding Avastin (bevacizumab) to a chemotherapy regimen with pemetrexed/cisplatin may not be a cost-effective choice to treat malignant pleural mesothelioma (MPM), according to a new Chinese study. The study, “Cost-effectiveness ... Read more

July 26, 2017July 26, 2017

Anetumab Ravtansine Is Unable to Outperform Vinorelbine as a Mesothelioma Treatment, Trial Shows

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Bayer’s anetumab ravtansine failed to improve the time it took for mesothelioma patients’ disease to progress, compared with another chemotherapy, according to a Phase 2 clinical trial. The results applied ... Read more

July 24, 2017July 24, 2017

P/D Surgery Less Detrimental to MPM Patients’ Quality of Life Than EPP, Study Finds

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Malignant pleural mesothelioma (MPM) patients who undergo pleurectomy (P/D) surgery usually live better and longer lives than those who have extrapleural pneumonectomy (EPP) surgery, finds a study featured in the Annals of Translational Medicine. ... Read more

July 20, 2017July 21, 2017

New-generation Radiation, Combined with Surgery, Is Effective Against Mesothelioma, Study Reports

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A new-generation radiation therapy introduced in 2007 is effective against malignant pleural mesothelioma, a New York study reports. The researchers at the Icahn School of Medicine at Mount Sinai said many ... Read more

July 19, 2017

Alimta and Tomudex Offer Same Combo Punch Against Mesothelioma, Study Shows

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A combination of Platinol and either of two antimetabolites delivers the same punch against mesothelioma, according to a study. The research, published in the Journal of Chemotherapy, compared a combination of ... Read more

July 18, 2017

Ibrance Combined with Specific Inhibitors Halts Mesothelioma Cell Growth, Study Reports

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Combining Ibrance with drugs that inhibit the PI3K pathway was found to stop the growth of malignant pleural mesothelioma (MPM) cells more effectively than treatment with Ibrance alone. Findings from the study, “Combined ... Read more

July 17, 2017

Researchers Call for Phase 3 Trials of CDK4/6 Inhibitors as Treatments for Malignant Mesothelioma

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CDK4/6 protein inhibitors, which have proven effective against some cancers, might be a way to treat malignant mesothelioma, according to a review in the journal Genes & Cancer. They called ... Read more

July 14, 2017

Phase 3 Nintedanib-Chemo Combo Trial Recruits Mesothelioma Patients for Global Study

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A Phase 3 trial is recruiting 450 participants at clinics worldwide to test whether nintedanib, used in combination with the standard chemotherapy drugs Alimta (pemetrexed) and Platinol (cisplatin) in patients with ... Read more

July 13, 2017July 27, 2017

Asbestos Substitute, Rock Wool Fiber, May Also Cause DNA Damage, Study Finds

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An asbestos alternative known as rock wool fiber may also cause DNA damage, according to a laboratory study conducted in China. The finding may be important because scientists say asbestos causes the lung ... Read more