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March 3, 2016March 3, 2016

Malignant Pleural Mesothelioma Study Finds Genetic Alterations in Tumors, Some with Possibility of Treatment

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Researchers involved in the International Mesothelioma Program at Brigham and Women’s Hospital (BWH), working with scientists at Genentech, analyzed hundreds of malignant pleural mesothelioma tumors and, through genomic analyses, found a ... Read more

March 2, 2016March 2, 2016

Therapy for Advanced Mesothelioma, Tremelimumab, Fails to Improve Survival in Clinical Trial, Company Reports

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AstraZeneca recently announced that the Phase 2b clinical trial evaluating tremelimumab monotherapy for the treatment of patients with unresectable malignant mesothelioma —the DETERMINE study — did not meet its primary endpoint of ... Read more

March 1, 2016March 1, 2016

Phase 2 Trial of New Mesothelioma Therapy, Using ImmunoGen’s ADC Technology, Getting Underway

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ImmunoGen, Inc. recently announced it has earned a milestone payment with Bayer’s initiation of a global Phase 2 clinical trial of anetumab ravtansine (BAY 94-9343) as a potential treatment for mesothelioma. ... Read more

February 29, 2016February 29, 2016

Mesothelioma Commercial Cell Lines Alone Not Suitable for Early Testing of New Drugs, Study Reports

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Researchers at the University of Leicester, U.K., investigated whether mesothelioma tumor cells grown in a dish are truly similar to the cells found in the human cancer, work important to the preclinical testing of ... Read more

February 26, 2016February 26, 2016

EPA Announces Final Cleanup Plan for Asbestos-related Superfund Site in Northwest Montana

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The U.S. Environmental Protection Agency (EPA) recently announced the final remedial plan for cleaning the Libby and Troy communities affected by the Libby Asbestos Superfund Site in Northwest Montana. The decision ... Read more

February 24, 2016February 26, 2016

Some Mesothelioma Cases of Unknown Origin Found to Point to Asbestos Exposure

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Researchers at the University of Milan re-evaluated hundreds of malignant mesothelioma (MM) cases that had been deemed “asbestos exposure unknown” in light of new knowledge regarding possible sources of asbestos. The team linked previously ... Read more

February 23, 2016February 23, 2016

Mesothelioma Applied Research Foundation to Award Grants to 5 New Research Projects

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The Mesothelioma Applied Research Foundation, a non-profit organization dedicated to finding a cure for mesothelioma and providing support for patients and families, announced that five research projects were the recipients ... Read more

February 16, 2016February 16, 2016

For Mesothelioma Treatment, an Immunotherapy-Based Approach Holds Promise

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A study published in the Journal of Translational Medicine showed that synthetic DNA sequences – called CpG-oligodeoxynucleotides (CpG-ODN) – can effectively halt the growth of human diffuse malignant peritoneal mesothelioma ... Read more

February 12, 2016February 12, 2016

Malignant Pleural Mesothelioma Found to Respond to New Chemo Combination

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A recent study presented the first case report of a malignant pleural mesothelioma patient effectively treated with a combination of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) and carboplatin. The study, titled “Repetitive responses to nanoparticle ... Read more

February 11, 2016February 11, 2016

In Malignant Pleural Mesothelioma, New Mutations in Gene Identified, Potentially Leading to Future Therapies

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Frequent mutations in the SETDB1 gene and genome-wide alterations of allelic loss were identified in malignant pleural mesothelioma, according to results of a recent study, “Whole exome and targeted deep ... Read more