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June 12, 2017June 12, 2017

Whole Exome Sequencing Reveals Similarities Between Asbestos-induced Mesothelioma Mice and Human Patients

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Whole exome sequencing of asbestos-induced mouse models of malignant mesothelioma (MM) is a genuine representation of human mesothelioma and is a valuable tool for further research into the development and ... Read more

June 9, 2017

Researchers Aim to Improve Diagnosis of Malignant Pleural Mesothelioma

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A study has tried to overcome the challenges in the diagnosis of patients with malignant pleural mesothelioma (MPM) through the detection of two biomarkers in pleural effusions and in peripheral blood ... Read more

June 8, 2017June 8, 2017

Calretinin Should Be Used as Blood-based Biomarker for Mesothelioma Detection, German Study Concludes

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The calcium-binding protein calretinin is useful as a blood-based biomarker with high sensitivity to detect malignant mesothelioma, finds a study, “Calretinin as a blood-based biomarker for mesothelioma,” that appeared in the journal BMC ... Read more

June 7, 2017

Nintedanib-Chemo Combo Increases Mesothelioma Patients’ Disease-Progression-Free Period

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Adding nintedanib to chemotherapy led to a 64 percent increase in the time it took for mesothelioma patients’ disease to progress, compared with chemo alone, according to updated results of ... Read more

June 6, 2017

Opdivo, Yervoy Combo Seem More Effective Than Standard Therapies in Relapsed MPM

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Immunotherapy may be the way to tackle malignant pleural mesothelioma (MPM) after relapse, a new Phase 2 trial suggests. Using Opdivo (nivolumab) alone or in combination with Yervoy (ipilimumab) was found to ... Read more

June 5, 2017June 5, 2017

Mathematical Modeling May Help Determine Best Treatment Schedules, Mesothelioma Study Shows

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French researchers have used mathematical modeling to select the best treatment schedule and dosing of Navelbine (vinorelbine) chemotherapy for mesothelioma and non-small cell lung cancer (NSCLC) patients. Their study, “Mathematical modelling ... Read more

June 1, 2017

Protein from Bullfrog May Have Therapeutic Potential for Mesothelioma Patients

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Researchers found that a protein with anti-cancer activity, which is isolated from the bullfrog, may be a good treatment option for mesothelioma, including in standard-of-care chemotherapy-resistant cancers. The protein, sialic ... Read more

May 31, 2017May 31, 2017

Tremelimumab, Imfinzi Combo Has Manageable Side Effects in Mesothelioma, Italian Trial Shows

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It is safe for malignant mesothelioma patients to combine Tremelimumab and Imfinzi (durvalumab), according to a study to be presented at the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting, set ... Read more

May 30, 2017

Complete Surgical Removal of Mesothelioma Tumor Can Prolong Survival, Review Says

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Complete surgical removal of mesothelioma tissue significantly prolongs survival in those with the cancer, according to researchers who reviewed a number of studies on this treatment approach. The longer survival occurred ... Read more

May 26, 2017May 26, 2017

ADI-PEG 20 Seen to Improve Response to Chemo in MPM Patients in Extension Trial

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Results from a Phase 1 extension study further confirmed the potential of ADI-PEG 20 to enhance the effectiveness of two chemotherapies — Platinol (cisplatin) and Alimta (pemetrexed) — commonly used to treat ... Read more