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April 27, 2017April 27, 2017

Curcumin, Found in Turmeric Plants, Seen to Shrink Sarcomatoid Mesothelioma Tumors in Rat Study

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Curcumin, a chemical found in turmeric plants, was more effective than suberanilohydroxamic acid, or SAHA, in reducing tumor mass in sarcomatoid malignant mesothelioma (MM) when tested in rats, and did ... Read more

April 26, 2017

Certain Prognostic Factor Can Predict Survival in Pleural Mesothelioma Patients, Analysis Finds

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A comprehensive review of the literature concludes that the neutrophil-to-lymphocyte ratio (NLR) is a factor can be used to predict overall survival in patients with malignant pleural mesothelioma (MPM). The ... Read more

April 25, 2017

Phase 1 Trial Suggests Tiziana’s Milciclib Benefits Mesothelioma Patients

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A combination of Tiziana Life Sciences‘ milciclib and the intravenous chemotherapy Gemzar (gemcitabine) stabilized tumor growth in a small group of patients with advanced solid tumors, including mesothelioma, according to a ... Read more

April 24, 2017

Tailored Treatment Options May Lead to Improved Outcomes in Mesothelioma Patients

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New research suggests that personalized treatment options based on a patient’s unique genetic biomarkers could lead to improved outcomes in cancer patients, including those suffering from mesothelioma. The study, “Clinical-pharmacogenetic ... Read more

April 21, 2017

Folic Acid Patterns Can Predict Mesothelioma Patients’ Response to Alimta, Study Suggests

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Patterns of folic acid activity in mesothelioma tumors can suggest whether a patient will respond to Alimta (pemetrexed), according to a study. The patterns, which appear in biomarkers of the activity, ... Read more

April 20, 2017April 20, 2017

Combination of Blood Biomarkers May Speed Diagnosis of Malignant Mesothelioma

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Detecting a combination of biomarkers already linked to malignant mesothelioma may significantly improve the sensitivity and specificity of screening tests, allowing a more accurate and reliable early diagnosis, new research reports. The study, “A ... Read more

April 19, 2017

Researchers Suggest Surface Molecules May Pair to Act as Diagnostic Biomarkers in Mesothelioma

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Researchers suggest that a cell surface molecule called CD44, and its interaction with a protein called hyaluronan, might be used as diagnostic biomarkers in malignant pleural mesothelioma, with the possibility ... Read more

April 18, 2017April 18, 2017

Midkine Protein Levels May Predict Prognosis in Mesothelioma Patients, Says Turkish Study

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Blood levels of the protein mesothelin have moderate sensitivity and high specificity in distinguishing malignant pleural mesothelioma (MPM) from other pleural diseases, but levels of a protein called midkine may ... Read more

April 17, 2017May 25, 2017

ADI-PEG 20, Chemo Triple Combo Promotes Cancer Cell Death in Some MPM Patients, Study Shows

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Depleting the amino acid arginine using a drug called ADI-PEG 20 enhances the efficacy of two well-established chemotherapy medications — Platinol (cisplatin) and Alimta (pemetrexed) — in patients with ASS1-deficient ... Read more

April 13, 2017April 13, 2017

Newly Identified Protein Variation May Make Mesothelioma More Vulnerable to Therapy, Study Reports

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A newly identified form of BRCA1-associated protein-1 (BAP1) increases malignant pleural mesothelioma cells’ vulnerability to some cancer therapies, a study indicates. The findings suggest a new strategy for treating patients ... Read more